HEPATOXIC EFFECT OF TRICLOSAN: A COMPREHENSIVE REVIEW

Abstract

This review explores the toxicity of Triclosan (TCS), a common antibacterial agent with widespread use in various products, including personal hygiene and medical items. The author concentrated on both experimental and non-experimental studies in this review on the toxicity of TCS. While generally deemed safe, evidences indicate that TCS exposure is linked to adverse environmental and health effects, including liver dysfunction, oxidative stress and endocrine disruption. Mechanistically, TCS disrupts cellular processes, compromises mitochondrial function, and alters metabolic pathways, potentially leading to conditions such as non-alcoholic fatty liver disease (NAFLD) and other liver-related disorders.